Autoimmune diseases are the result of a process in which the immune system mistakes an organ or body system for an invader, and attacks it as such. This results in inflammation and damage to the organ.
Autoimmune Hepatitis
The immune system is involved in one way or another in patients with many types of hepatitis, which is an inflammation of the liver. For people with chronic viral hepatitis, the immune system attacks the virus and the resulting long-term inflammation can cause damage to the liver.
Autoimmune hepatitis, when the body’s immune system mistakes normal liver tissue for an invader and attacks accordingly, is a chronic disease that causes inflammation and liver damage. If left untreated, autoimmune hepatitis can worsen over time and lead to cirrhosis and liver failure. The disease can cause symptoms that resemble those of viral or other types of hepatitis such as:
Fatigue Joint pain Nausea Loss of appetite Pain or discomfort over the liver Skin rashes Dark yellow urine Light-colored stools Jaundice, or yellowing of the skin and whites of the eyes
Vaccines
There are currently two vaccines to prevent against two different types of viral hepatitis—hepatitis A and hepatitis B. Vaccines, or immunizations, use a trigger (such as inactivated or weakened viral material) to create an immune response against the invader. The immune system then essentially has a developed and effective response available when a true pathogen becomes a threat.
Treatments
For patients with autoimmune hepatitis, the goal of treatment is to prevent liver damage that occurs as a result of the immune system’s assault on the liver. One way modern medicine is able to achieve this goal is by using treatments, such as steroids or steroids plus azathioprine, that suppress the immune system to help prevent further damage.